The 2013 Nobel Prize for Chemistry has been awarded to Martin Karplus, Michael Levitt and Arieh Warshel for their development of computer models of complex chemical systems. All three researchers have close links to physics. Karplus, who is a US and Austrian citizen, originally studied physics and chemistry at Harvard University and is now based there and at the University of Strasbourg. Levitt, who has a physics degree from King's College London, is a US and UK citizen working at Stanford University, while Warshel is a US and Israeli citizen based at the University of Southern California. The trio will share the SEK 8m (£775,000) and will receive their medals at a ceremony in Stockholm on 10 December.
Karplus, Levitt and Warshel won the prize for developing computational techniques that use both classical and quantum physics to describe complex chemical processes. Chemical models based on classical physics are relatively easy to compute and can therefore be used to simulate some aspects of the behaviour of large molecules such as proteins. The problem, however, is that these classical models cannot describe crucial aspects of chemistry such as how reactions proceed. To do so requires models based on quantum mechanics, which in turn need huge amounts of computing power. Quantum simulations can therefore only be applied to relatively small molecules.
Physics World: Chemistry Nobel honors trio who combined classical and quantum physics
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