ethics (2)

Pandora's Box...

gene-leak.jpg
MS TECH / SOURCE PHOTO: GETTY

 

Topics: Biology, Biotechnology, Civics, Ethics, Existentialism


A private DNA ancestry database that’s been used by police to catch criminals is a security risk from which a nation-state could steal DNA data on a million Americans, according to security researchers.

Security flaws in the service, called GEDmatch, not only risk exposing people’s genetic health information but could let an adversary such as China or Russia create a powerful biometric database useful for identifying nearly any American from a DNA sample.

GEDmatch, which crowdsources DNA profiles, was created by genealogy enthusiasts to let people search for relatives and is run entirely by volunteers. It shows how a trend toward sharing DNA data online can create privacy risks affecting everyone, even people who don’t choose to share their own information.

“You can replace your credit card number, but you can’t replace your genome,” says Peter Ney, a postdoctoral researcher in computer science at the University of Washington.

Ney, along with professors and DNA security researchers Luis Ceze and Tadayoshi Kohno, described in a report posted online how they developed and tested a novel attack employing DNA data they uploaded to GEDmatch.

 

The DNA database used to find the Golden State Killer is a national security leak waiting to happen
Antonio Regalado, Technology Review

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Ethics of Genesis...

MS. TECH; EVOLUTION: WIKIMEDIA COMMONS

 

Topics: Biology, Ethics, Genetics, Science Fiction


Note: The article "went there" before I could.

"Beware the beast man, for he is the devil's pawn. Alone among God's primates, he kills for sport or lust or greed. Yea, he will murder his brother to possess his brother's land. Let him not breed in great numbers, for he will make a desert of his home, and yours. Shun him... for he is the harbinger of death." Internet Movie Database, Planet of the Apes (1968) Synopsis

 

*****


Human intelligence is one of evolution’s most consequential inventions. It is the result of a sprint that started millions of years ago, leading to ever bigger brains and new abilities. Eventually, humans stood upright, took up the plow, and created civilization, while our primate cousins stayed in the trees.

Now scientists in southern China report that they've tried to narrow the evolutionary gap, creating several transgenic macaque monkeys with extra copies of a human gene suspected of playing a role in shaping human intelligence.

“This was the first attempt to understand the evolution of human cognition using a transgenic monkey model,” says Bing Su, the geneticist at the Kunming Institute of Zoology who led the effort.

According to their findings, the modified monkeys did better on a memory test involving colors and block pictures, and their brains also took longer to develop—as those of human children do. There wasn’t a difference in brain size.

Su’s monkeys raise some unusual questions about animal rights. In 2010, Sikela and three colleagues wrote a paper called “The ethics of using transgenic non-human primates to study what makes us human,” in which they concluded that human brain genes should never be added to apes, such as chimpanzees, because they are too similar to us.

“You just go to the Planet of the Apes immediately in the popular imagination,” says Jacqueline Glover, a University of Colorado bioethicist who was one of the authors. “To humanize them is to cause harm. Where would they live and what would they do? Do not create a being that can’t have a meaningful life in any context.”

 

*****


Not to go all Cassandra on you, but...

At the story's heart is Caesar (Andy Serkis), a chimpanzee who gains human-like intelligence and emotions from an experimental drug. Raised like a child by the drug's creator, Will Rodman (James Franco) and a primatologist Caroline Aranha (Freida Pinto), Caesar ultimately finds himself taken from the humans he loves and imprisoned in an ape sanctuary in San Bruno. Seeking justice for his fellow inmates, Caesar gives the fellow apes the same drug that he inherited. He then assembles a simian army and escapes the sanctuary - putting man and ape on a collision course that could change the planet forever. Internet Movie Database, Rise of the Planet of the Apes (2011) Storyline

 

Chinese scientists have put human brain genes in monkeys—and yes, they may be smarter
Antonio Regalado, MIT Technology Review

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