Reginald L. Goodwin's Posts (3119)

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Jaime Escalante...



Jaime Escalante was born December 31, 1930 in La Paz, Bolivia. He came to the United States in the 1960s to seek a better life. He began teaching math to troubled students in a violent Los Angeles school and became famous for leading many of them to pass the advanced placement calculus test. He was played by Edward James Olmos in the film Stand and Deliver. He died of cancer on March 30, 2010.

Professional Career

In 1974, Escalante took a job at Garfield High School in East Los Angeles, California. He found himself in a challenging situation: teaching math to troubled students in a rundown school known for violence and drugs. While some had dismissed the students as "unteachable," Escalante strove to reach his students and to get them to live up to their potential. He started an advanced mathematics program with a handful of students.

In 1982, his largest class of students took and passed an advanced placement test in Calculus. Some of the students' test scores were invalidated by the testing company because it believed that the students had cheated. Escalante protested, saying that the students had been disqualified because they were Hispanic and from a poor school. A few months later many of the students retook the test and passed, proving that they knew the material and that the company was wrong.

Biography: Jaime Escalante

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Quantum Physics for Everyone...

Innovative outreach. (a) From 18 October to 30 October 2011, visitors approaching the Eiffel Tower from Trocadéro square might have encountered a model in which each of three tower sections levitates above a superconducting ceramic. By bringing such displays to the heart of Paris, French physicists hoped to engage segments of the public not usually attracted by science outreach activities. (b) Artists and designers helped produce hands-on projects that introduce young people to quantum physics. In one such activity, children create the field of a magnet levitating above a superconductor.

...and, why not?

The very venue of this monologue/blog is courtesy of the photoelectric effect (Einstein); he and Heisenberg et al brought us Quantum Mechanics - to Einstein's chagrin - which allows us to design cell phones, laptops, I-pads, flat screens, the Internet...pretty much the modern age. I'm often amused at the rants directed at science on social media platforms PROVIDED by that same science. The irony is delicious...

For condensed-matter physicists, the year 2011 was a very special one. It marked the 100th anniversary of the discovery of superconductivity, one of the most fascinating topics in quantum physics and still one of the most studied. When certain materials—for example, aluminum and lead—are cooled to nearly absolute zero, they suddenly conduct electricity perfectly, with no resistance. Superconductors also expel magnetic fields, a property that causes magnets to levitate on top of superconductors. Even more fascinating, under certain conditions, the magnet becomes “pinned” to the superconductor. In that case, it can either levitate above the superconductor or remain suspended below it.

The superconductivity that kicks in at very low temperature was explained in the 1960s by John Bardeen, Leon Cooper, and J. Robert Schrieffer with what is now called the BCS model. However, more recently discovered families of superconductors conduct perfectly at temperatures up to 10 times that of the usual metals. The BCS model does not seem to apply to those high-temperature superconductors, hence the continuing research. Ultimately, physicists hope to discover a material that superconducts at room temperature.

As part of the centenary celebration, the French research agency CNRS asked researchers in the field to introduce superconductivity to the greater public. We were immediately enthusiastic, but two worries soon came to mind: Isn’t quantum physics too complex to be explained to the general public? And in any case, are people really interested? Some public relations experts warned us that fundamental physics is not as appealing as it used to be. Now, they said, is the time to be talking about neurology or climatology. Interest in physics relates only to applications and new technologies.

Despite those warnings, we spent a year trying to show and explain superconductivity and quantum physics in a great variety of places and to all kinds of people—teenagers, younger children, students, parents, artists, journalists, and more. And we used all sorts of means, including websites, exhibits, movies, YouTube, live demonstrations, conferences, and science fairs. What we discovered was a surprise to most of us.

Bad news first

One lesson we learned was that if you stick to conventional outreach tools and actions, you will end up with a conventional outreach public, namely, people already interested in and familiar with science. We developed pedagogical exhibits and movies to explain superconductivity, a flyer, demonstrations, and even a website. Such content was useful for teachers and students in an academic setting, but it did not work that well for the general public. Our 10-panel exhibit with photos and images was a great decoration in science museums, science fairs, and school halls, but people did not actually spend time reading the content beyond the introductory panel. Our information-packed website attracts about 300 new visitors daily, but the average visiting time is less than 2 minutes. The 11-minute movie we made is just too long for people now used to YouTube videos. We realized too late that the internet has profoundly changed peoples’ capacity to focus and read for more than a minute. Or perhaps people have long had a minuscule attention span.

A second bit of bad news is that outreach conferences do not reach a wide public. We organized many conferences all over France with well-trained, animated speakers who presented great slides and even live experiments. The rooms were often full of enthusiastic participants. But we discovered that the audience was mostly composed of the speakers’ colleagues and their families, engineers, physics students, and retired scientists—essentially scientifically literate people already convinced of the importance of fundamental physics.

American Institute of Physics: Quantum Physics for Everyone
Related site: Quantum Made Easy

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Ellen Ochoa...



1st Hispanic Female Astronaut: text source here


Ellen Ochoa was born on May 10, 1958 in Los Angeles, CA. She received her bachelor of science degree in physics from San Diego State University, and a master of science degree and doctorate in electrical engineering from Stanford University.

Ellen Ochoa’s pre-doctoral work at Stanford University in electrical engineering led to the development of an optical system designed to detect imperfections in repeating patterns. This invention patented in 1987, can be used for quality control in the manufacturing of various intricate parts. Dr. Ellen Ochoa later patented an optical system which can be used to robotically manufacture goods or in robotic guiding systems. In all, Ellen Ochoa has received three patents most recently one in 1990.

In addition to being an inventor, Dr. Ellen Ochoa is also a research scientist and astronaut for NASA. Selected by NASA in January 1990, Dr. Ellen Ochoa is a veteran of three space flights. She has logged over 719 hours in space, her most recent mission was a 10 day mission aboard the space shuttle Discovery in May of 1999.

NASA bio: Ellen Ochoa, PhD, Director: Lyndon B. Johnson Space Center

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Starting Abacus...

Tube chip: This scanning electron microscopy image shows a section of the first-ever carbon nanotube computer. The image was colored to identify different parts of the chip.

For the first time, researchers have built a computer whose central processor is based entirely on carbon nanotubes, a form of carbon with remarkable material and electronic properties. The computer is slow and simple, but its creators, a group of Stanford University engineers, say it shows that carbon nanotube electronics are a viable potential replacement for silicon when it reaches its limits in ever-smaller electronic circuits.



The carbon nanotube processor is comparable in capabilities to the Intel 4004, that company’s first microprocessor, which was released in 1971, says Subhasish Mitra, an electrical engineer at Stanford and one of the project’s co-leaders. The computer, described today in the journal Nature, runs a simple software instruction set called MIPS. It can switch between multiple tasks (counting and sorting numbers) and keep track of them, and it can fetch data from and send it back to an external memory.



The nanotube processor is made up of 142 transistors, each of which contains carbon nanotubes that are about 10 to 200 nanometer long. The Stanford group says it has made six versions of carbon nanotube computers, including one that can be connected to external hardware—a numerical keypad that can be used to input numbers for addition.

MIT Technology Review: The First Carbon Nanotube Computer

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Santiago Ramón y Cajal...



The Nobel Prize in Physiology or Medicine 1906

Camillo Golgi, Santiago Ramón y Cajal

Santiago Ramón y Cajal

Born: 1 May 1852, Petilla de Aragó, Spain

Died: 17 October 1934, Madrid, Spain

Affiliation at the time of the award: Madrid University, Madrid, Spain

Prize motivation: "in recognition of their work on the structure of the nervous system"

Santiago Ramón y Cajal was born on May 1, 1852, at Petilla de Aragón, Spain. As a boy he was apprenticed first to a barber and then to a cobbler. He himself wished to be an artist - his gift for draughtsmanship is evident in his published works. His father, however, who was Professor of Applied Anatomy in the University of Saragossa, persuaded him to study medicine, which he did, chiefly under the direction of his father. (Later, he made drawings for an atlas of anatomy which his father was preparing, but which was never published.)

In 1873 he took his Licentiate in Medicine at Saragossa and served, after a competitive examination, as an army doctor. He took part in an expedition to Cuba in 1874-75, where he contracted malaria and tuberculosis. On his return he became an assistant in the School of Anatomy in the Faculty of Medicine at Saragossa (1875) and then, at his own request, Director of the Saragossa Museum (1879). In 1877 he obtained the degree of Doctor of Medicine at Madrid and in 1883 he was appointed Professor of Descriptive and General Anatomy at Valencia. In 1887 he was appointed Professor of Histology and Pathological Anatomy at Barcelona and in 1892 he was appointed to the same Chair at Madrid. In 1900-1901 he was appointed Director of the «Instituto Nacional de Higiene» and of the «Investigaciones Biológicas».

In 1880 he began to publish scientific works, of which the following are the most important: Manual de Histología normal y Técnica micrográfica (Manual of normal histology and micrographic technique), 1889 (2nd ed., 1893). A summary of this manual recast with additions, appeared under the title Elementos de Histología, etc. (Elements of histology, etc.), 1897; Manual de Anatomía patológica general (Manual of general pathological anatomy), 1890 (3rd ed., 1900). In addition may be cited: Les nouvelles idées sur la fine anatomie des centres nerveux (New ideas on the fine anatomy of the nerve centres), 1894; Textura del sistema nervioso del hombre y de los vertebrados (Textbook on the nervous system of man and the vertebrates), 1897-1899; Die Retina der Wirbelthiere (The retina of vertebrates), 1894.

Apart from these works Cajal has published more than 100 articles in French and Spanish scientific periodicals, especially on the fine structure of the nervous system and especially of the brain and spinal cord, but including also that of muscles and other tissues, and various subjects in the field of general pathology. These articles are dispersed in numerous Spanish journals and various specialized journals of other countries (especially French ones).

Nobel Prize:

Biographical, Nobel Lecture, Photo Gallery

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Severo Ochoa...



The Nobel Prize in Physiology or Medicine 1959

Severo Ochoa, Arthur Kornberg

Born: 24 September 1905, Luarca, Spain

Died: 1 November 1993, Madrid, Spain

Affiliation at the time of the award: New York University, College of Medicine, New York, NY, USA

Prize motivation: "for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid"

Severo Ochoa was born at Luarca, Spain, on September 24th, 1905. He is the son of Severo Ochoa, a lawyer and business man, and Carmen de Albornoz.

Ochoa was educated at Málaga College, where he took his B.A. degree in 1921.* His interest in biology was greatly stimulated by the publications of the great Spanish neurologist, Ramón y Cajal, and he went to the Medical School of the University of Madrid, where he obtained his M.D. degree (with honours) in 1929. While he was at the University he was Assistant to Professor Juan Negrin and he paid, during the summer of 1927, a visit to the University of Glasgow to work under Professor D. Noel Paton.

After graduating in 1929 Ochoa went, with the aid of the Spanish Council of Scientific Research, to work under Otto Meyerhof at the Kaiser Wilhelm Institut für Medizinische Forschung at Heidelberg. During this period he worked on the biochemistry and physiology of muscle, and his outlook and training were decisively influenced by Meyerhof.

In 1931, Ochoa was appointed Lecturer in Physiology at the University of Madrid, a post he held until 1935. In 1932 he went to the National Institute for Medical Research, London, where he worked with Dr. H. W. Dudley on his first problem in enzymology.

Returning to Madrid in 1934, he was appointed Lecturer in Physiology and Biochemistry there and later became Head of the Physiology Division of the Institute for Medical Research, Madrid. In 1936 he was appointed Guest Research Assistant in Meyerhof's Laboratory at Heidelberg, where he worked on some of the enzymatic steps of glycolysis and fermentation. In 1937 he held a Ray Lankester Investigatorship at the Plymouth Marine Biological Laboratory and from 1938 until 1941 he worked on the biological function of vitamin B1 with Professor R. A. Peters at Oxford University, where he was appointed Demonstrator and Nuffield Research Assistant.

While he was at Oxford he became interested in the enzymatic mechanisms of oxidative metabolism and in 1941 he went to America and worked, until 1942, at the Washington University School of Medicine, St. Louis, where he was appointed Instructor and Research Associate in Pharmacology and worked with Carl and Gerty Cori on problems of enzymology. In 1942 he was appointed Research Associate in Medicine at the New York University School of Medicine and there subsequently became Assistant Professor of Biochemistry (1945), Professor of Pharmacology (1946), Professor of Biochemistry (1954), and Chairman of the Department of Biochemistry. In 1956 he became an American citizen.

Nobel Prize:

Biographical, Nobel Lecture, Banquet Speech

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Tall in the Saddle...

The top image shows the full sky map as seen by Planck – the CMB temperature fluctuations on large scales are more extreme on the right side of the sky. The bottom image illustrates our bubble universe being born from the larger universe (depicted only by the blue background). Our bubble forms at time T0 and expands outwards, as shown with red rings at times T1, T2 and T3. In the 3D space–time, this expansion forms a "bubble wall" that acts as the starting point (t0) of our universe. Subsequent times (t1, t2, t3) are defined on hypersurfaces above the bubble wall. The yellow lines show the trajectories of constant positions in space inside this open universe. (Courtesy: ESA and the Planck Collaboration/Alan Stonebraker, Phys. Rev.Lett.)

The geometry of the universe is "open" or negatively curved like a saddle, according to a new model proposed by researchers in Europe who have studied anomalies in the cosmic microwave background radiation. The anomalies were first detected by NASA's Wilkinson Microwave Anisotropy Probe (WMAP) in 2004 and were confirmed earlier this year by the European Space Agency's Planck space mission.



Cosmologists believe that when the universe was very young – a mere 10–35 s after the Big Bang – it underwent a period of extremely rapid expansion known as "inflation". About 380,000 years after the Big Bang, the cosmic microwave background (CMB) – the thermal remnant of the Big Bang – came into being. Physicists had expected the temperature of the CMB to be the same everywhere but for almost 10 years, evidence of a puzzling CMB anomaly has grown. It is becoming clear that the experimentally observed temperature fluctuations in the two hemispheres of the sky are slightly different. This means that the density of matter and energy seems to vary more strongly on one side of the sky than on the other.

Physics World: Is the universe saddle shaped?

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Mario J. Molina...



The Nobel Prize in Chemistry 1995

Paul J. Crutzen, Mario J. Molina, F. Sherwood Rowland

Born: 19 March 1943, Mexico City, Mexico

Affiliation at the time of the award: Massachusetts Institute of Technology (MIT), Cambridge, MA, USA

Prize motivation: "for their work in atmospheric chemistry, particularly concerning the formation and decomposition of ozone"

Field: Atmospheric and environmental chemistry

I attended elementary school and high school in Mexico City. I was already fascinated by science before entering high school; I still remember my excitement when I first glanced at paramecia and amoebae through a rather primitive toy microscope. I then converted a bathroom, seldom used by the family, into a laboratory and spent hours playing with chemistry sets. With the help of an aunt, Esther Molina, who was a chemist, I continued with more challenging experiments along the lines of those carried out by freshman chemistry students in college. Keeping with our family tradition of sending their children abroad for a couple of years, and aware of my interest in chemistry, I was sent to a boarding school in Switzerland when I was 11 years old, on the assumption that German was an important language for a prospective chemist to learn. I remember I was thrilled to go to Europe, but then I was disappointed in that my European schoolmates had no more interest in science than my Mexican friends. I had already decided at that time to become a research chemist; earlier, I had seriously contemplated the possibility of pursuing a career in music - I used to play the violin in those days. In 1960, I enrolled in the chemical engineering program at UNAM, as this was then the closest way to become a physical chemist, taking math-oriented courses not available to chemistry majors.

After finishing my undergraduate studies in Mexico, I decided to obtain a Ph.D. degree in physical chemistry. This was not an easy task; although my training in chemical engineering was good, it was weak in mathematics, physics, as well as in various areas of basic physical chemistry - subjects such as quantum mechanics were totally alien to me in those days. At first I went to Germany and enrolled at the University of Freiburg. After spending nearly two years doing research in kinetics of polymerizations, I realized that I wanted to have time to study various basic subjects in order to broaden my background and to explore other research areas. Thus, I decided to seek admission to a graduate program in the United States. While pondering my future plans, I spent several months in Paris, where I was able to study mathematics on my own and I also had a wonderful time discussing all sorts of topics, ranging from politics, philosophy, to the arts, etc., with many good friends. Subsequently, I returned to Mexico as an Assistant Professor at the UNAM and I set up the first graduate program in chemical engineering. Finally, in 1968 I left for the University of California at Berkeley to pursue my graduate studies in physical chemistry.

Nobel Prize:

Biographical, Nobel Lecture, Interview (32 minutes)

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Atomic Friction...



A new experimental method based on atomic force microscopy allows the investigation of friction at the scale of individual atoms.



Everyone learns the basics of friction in high-school physics classes: the friction force experienced by a sliding object is proportional to the normal force that an object exerts on a surface. Remarkably, this extremely simple and empirical relation, known as Amontons’ Law, is still often used in creating the most technologically sophisticated machines and devices, even though friction is known to vary with a large number of other parameters not captured in this relation. For example, at the nanoscale, friction is significantly influenced by adhesion, an example where Amontons’ Law cannot predict the friction force [1]. Likewise, friction can depend on sliding speed, duration of contact, environment, temperature, and the sliding direction [1, 2]. As reported in Physical Review Letters, Jay Weymouth and colleagues at the University of Regensburg in Germany have investigated the friction force at atomic length scales, using an atomic force microscope (AFM) [3] to probe the forces between a tungsten tip coated with a small amount of silicon, sliding on the surface of crystalline silicon. They report an observation never before obtained at the scale of just a few atoms: friction is strongly dependent on the orientation of specific silicon atomic bonds at the surface with respect to the sliding direction of the tip.



A directional dependence of friction, also known as friction anisotropy, has been previously observed on larger scales (at least a few nanometers). For example, a tip was pulled along a molecular layer where the molecules were locally all tilted in the same direction. Sliding along the tilt axis produced lower friction than when sliding perpendicular to it [4]. A similar behavior can be observed in a simple way by pressing one’s hands together (as if in prayer but with the fingers spaced apart). Upon sliding the fingers of the left hand against the fingers of right hand (perpendicular to the long axis of your fingers), the fingers of one hand become stuck in between those of the other. However, if one instead slides the left hand down and the right hand up (parallel to the long axis of your fingers), the hands move smoothly. The relative orientation between the sliding direction and the grooves of one’s fingers influences friction because of the geometry of our hands. Friction anisotropy has been observed by sliding a small tip on atomically flat and well-characterized surfaces [5]. However, in all these cases, the nanometer-size tip was pressed into contact with the surface, meaning that a large number (at least thousands) of atoms were in contact during this experiment.

American Physical Society: Friction at the Atomic Scale

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César Milstein...



The Nobel Prize in Physiology or Medicine 1984

Niels K. Jerne, Georges J.F. Köhler, César Milstein

Born: 8 October 1927, Bahia Blanca, Argentina

Died: 24 March 2002, Cambridge, United Kingdom

Affiliation at the time of the award: MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

Prize motivation: "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies"

My father was a Jewish immigrant who settled in Argentina, and was left to his own devices at the age of 15. My mother was a teacher, herself the daughter of a poor immigrant family. For both my mother and my father, no sacrifice was too hard to make sure that their three sons (I was the middle one) would go to university. I wasn't a particularly brilliant student, but on the other hand I was very active in Student Union affairs and in student politics. It was in this way that I met my wife, Celia. After graduation, we married, and took a full year off in a most unusual and romantic honeymoon, hitch-hiking our way through most countries in Europe, including a couple of months working in Israel kibbutzim. As we returned to Argentina, I started seriously to work towards a doctoral degree under the direction of Professor Stoppani, the Professor of Biochemistry at the Medical School. My PhD thesis work was done with no economic support. Both Celia and I worked part-time doing clinical biochemistry, between us earning just enough to keep us going. My thesis was on kinetics studies with the enzyme aldehyde dehydrogenase. When that was finished, I was granted a British Council Fellowship to work under the supervision of Malcolm Dixon.

Nobel Prize:

Biographical, Nobel Lecture, Documentary (1 min)

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Firmly Aboard the Pequod...


The most prescient portrait of the American character and our ultimate fate as a species is found in Herman Melville’s “Moby Dick.” Melville makes our murderous obsessions, our hubris, violent impulses, moral weakness and inevitable self-destruction visible in his chronicle of a whaling voyage. He is our foremost oracle. He is to us what William Shakespeare was to Elizabethan England or Fyodor Dostoyevsky to czarist Russia.

Our country is given shape in the form of the ship, the Pequod, named after the Indian tribe exterminated in 1638 by the Puritans and their Native American allies. The ship’s 30-man crew—there were 30 states in the Union when Melville wrote the novel—is a mixture of races and creeds. The object of the hunt is a massive white whale, Moby Dick, which, in a previous encounter, maimed the ship’s captain, Ahab, by biting off one of his legs. The self-destructive fury of the quest, much like that of the one we are on, assures the Pequod’s destruction. And those on the ship, on some level, know they are doomed—just as many of us know that a consumer culture based on corporate profit, limitless exploitation and the continued extraction of fossil fuels is doomed.

Chris Hedges, "We Are All Aboard the Pequod"

Houston Chronicle: Texas lawmakers on Tuesday began weighing changes to the state’s high school graduation requirements to give students more flexibility in which courses they must take.

A closely watched bill by Sen. Dan Patrick, R-Houston, would change the default graduation plan so students would not necessarily have to take four years of English, math, science and social studies. Instead, they could specialize in areas such as arts and humanities or science, technology, engineering and math.

“My focus is to help stem the dropout rate,” Patrick said during a meeting Tuesday, explaining that students would be able to take more courses that interest them.

Lake Houston Observer: Assessments in Algebra II, geometry, English III, chemistry, physics, world geography, and world history have been eliminated from the testing requirements. As a result, the July 2013 STAAR administration will not include assessments for these courses. End-of-course assessments will continue to be offered in Algebra I, English I, English II, biology, and U.S. history.

Texas is a large market due to its sheer size. Thus, a lot of other states emulate them; based their textbook purchase decisions on what they deem are deliberative, informed educational moves.

This was alerted to me by a friend on Facebook. My description/reaction is as follows:

"So, biology only is going to help us design an I-phone? Ye gods, we are destroyed by ideology, lunacy and idiocy! The only "logic" I can see in this: physics and chemistry would destroy their creationist/intelligent design garbage narrative I've read they're trying to get in textbooks K-12. Texas influences a lot of education markets nationally that assume it following a rational course, which this is NOT."

We seem all firmly aboard the Pequod, 'tossed to and fro by every wind of doctrine' (Ephesians 4:14); the ship of fools captained by a 1% Ahab fighting against the forces of nature and common sense. Anything that should be eliminated is the testing-industrial-complex, not science in an ever-increasing; ever-complicated world. We need more scientists, mathematicians, engineers and technologists with an appreciation for written discourse, geography and history; more importantly: a citizenry that appreciates these subjects and informed enough to demand such from its leaders and hold them accountable. A canyon gap between 1 and 99% will soon be an untraversable chasm. I do not see a stable society emerging from this Phoenix's ashes.

Controversies are manufactured to keep us divided: "Smokey James: ['Blue Collar' voice over echoing earlier line] They pit the lifers against the new boy and the young against the old. The black against the white. Everything they do is to keep us in our place." A fill-in-the-blank modern extrapolation is pretty simple.

Chris Hedges opined on climate change, which takes an appreciation of science. The conclusions of science have long been opposed since Galileo as it destroys the narrative of authoritarians in sheep and shepherds' clothing (Canis Lupus would be too obvious), more driven by their warped sense of order and power than any concern...as sociopaths lack empathy nor real concern for the well-being of their fellow humankind, spiritual and scientific efficacy in this country.

Shoulders thrown into the effort of rowing; brine spraying our collective faces, we steady our feet above deck as someone shouts:

"There she blows!--there she blows! A hump like a snow-hill! It is Moby Dick!"

"Hereby perhaps Stubb indirectly hinted, that though man loved his fellow, yet man is a money-making animal, which propensity too often interferes with his benevolence."

"From hell's heart I stab at thee; for hate's sake I spit my last breath at thee."

"Ignorance is the parent of fear."

There she blows, a great force of nature and alas, we cannot all be Ishmael...

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Luis Federico Leloir...



The Nobel Prize in Chemistry 1970
Luis Leloir

Luis F. Leloir

Born: 6 September 1906, Paris, France

Died: 2 December 1987, Buenos Aires, Argentina

Affiliation at the time of the award: Institute for Biochemical Research, Buenos Aires, Argentina

Prize motivation: "for his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates"

Field: Biochemistry

Luis F. Leloir was born in Paris of Argentine parents on September 6, 1906 and has lived in Buenos Aires since he was two years old. He graduated as a Medical Doctor in the University of Buenos Aires in 1932 and started his scientific career at the Institute of Physiology working with Professor Bernardo A. Houssay on the role of the adrenalin carbohydrate metabolism. In 1936 he worked at the Biochemical Laboratory of Cambridge, England, which was directed by Sir Frederick Gowland Hopkins. There he collaborated with Malcom Dixon, N.L. Edson and D.E. Green. On returning to Buenos Aires he worked with J.M. Muñoz on the oxidation of fatty acids in liver, and also together with E. Braun Menéndez, J.C. Fasciolo and A.C. Taquini on the formation of angiotensin. In 1944 he was Research Assistant in Dr. Carl F. Cori's laboratory in St. Louis, United States and thereafter worked with D.E. Green in the College of Physicians and Surgeons, Columbia University, New York. Since then he has been Director of the Instituto de Investigaciones Bioquímicas, Fundación Campomar. With his early collaborators, Ranwel Caputto, Carlos E. Cardini, Raúl Trucco and Alejandro C. Paladini work was started on the metabolism of galactose which led to the isolation of glucose 1,6-diphosphate and uridine diphosphate glucose. The latter substance was then found to act as glucose donor in the synthesis of trehalose (with Enrico Cabib, 1953 ) and sucrose (with Carlos E. Cardini and J.Chiriboga, 1955). Other sugar nucleotides such as uridine diphosphate acetylglucosamine and guanosine diphosphate mannose were also isolated. Further work showed that uridine diphosphate glucose is involved in glycogen synthesis and adenosine diphosphate glucose in that of starch.

Nobel Prize:

Biographical, Nobel Lecture, Banquet Speech

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Photonic Bernoulli Forces...



ABSTRACT:
By Bernoulli's law, an increase in the relative speed of a fluid around a body is accompanies by a decrease in the pressure. Therefore, a rotating body in a fluid stream experiences a force perpendicular to the motion of the fluid because of the unequal relative speed of the fluid across its surface. It is well known that light has a constant speed irrespective of the relative motion. Does a rotating body immersed in a stream of photons experience a Bernoulli-like force? We show that, indeed, a rotating dielectric cylinder experiences such a lateral force from an electromagnetic wave. In fact, the sign of the lateral force is the same as that of the fluid-mechanical analogue as long as the electric susceptibility is positive (ε>ε0), but for negative-susceptibility materials (e.g. metals) we show that the lateral force is in the opposite direction. Because these results are derived from a classical electromagnetic scattering problem, Mie-resonance enhancements that occur in other scattering phenomena also enhance the lateral force.

Physics arXiv: Optical "Bernoulli" Forces

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Bernardo Alberto Houssay...



The Nobel Prize in Physiology or Medicine 1947
Carl Cori, Gerty Cori, Bernardo Houssay

Bernardo Alberto Houssay

Born: 10 April 1887, Buenos Aires, Argentina

Died: 21 September 1971, Buenos Aires, Argentina

Affiliation at the time of the award: Instituto de Biologia y Medicina Experimental (Institute for Biology and Experimental Medicine), Buenos Aires, Argentina

Prize motivation: "for his discovery of the part played by the hormone of the anterior pituitary lobe in the metabolism of sugar"

Bernardo Alberto Houssay was born in Buenos Aires, Argentina, on April 10, 1887, one of the eight children of Dr. Albert and Clara (née Laffont) Houssay, who had come to Argentina from France. His father was a barrister. His early education was at a private school, the Colegio Británico. He then entered the School of Pharmacy of the University of Buenos Aires at the exceptionally early age of 14, graduating in 1904. He had already begun studying medicine and, in 1907, before completing his studies, he took up a post in the Department of Physiology. He began here his research on the hypophysis which resulted in his M.D.-thesis (1911), a thesis which earned him a University prize.

In 1910 he was appointed Professor of Physiology in the University's School of Veterinary Medicine. During this time he had been doing hospital practice and, in 1913, became Chief Physician at the Alvear Hospital. In addition to this he was also in charge of the Laboratory of Experimental Physiology and Pathology in the National Department of Hygiene from 1915 to 1919. In 1919 he became Professor of Physiology in the Medical School at Buenos Aires University. He also organized the Institute of Physiology at the Medical School, making it a centre with an international reputation. He remained Professor and Director of the Institute until 1943. In this year the Government then in power deprived him of his post, as a result of his voicing his opinion that there should be effective democracy in the country. Although receiving many invitations from abroad, he continued his work in an institute which he organized with the support of funds contributed by the Sauberan Foundation and other bodies. This was the Instituto de Biología y Medicina Experimental, where he still remains as Director. In 1955 a new Government reinstated him in the University.

Nobel Prize:

Biographical, Nobel Lecture, Banquet Speech

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On The Brane...



This challenges a holy grail of physics, and relates to The Standard Model; how we describe the four forces of nature and how they interact, even the Higgs Boson.

I almost hesitate to post it because many who do not "believe in the Big Bang Theory" will shout: aha! I say: ah, science - self-examining, exploring; learning more tomorrow than we thought we knew yesterday. Quantum mechanics had its trials and tribulations: Weins Law, Rayleigh-Jeans Law and the "ultraviolet catastrophe" eventually getting to Max Planck (of Planck's constant) and light seen as quanta. This eventually led to Einstein and the photoelectric effect in his Annus mirabilis papers generated in a lowly patent office in Munich. Thus we have the Internet, I-phones, flat screens, etc.

This description matches some of the wording I've seen over the years of the "universe as hologram" and admittedly either didn't understand or regarded as new age mystic pop culture. This challenge will have to be peer-reviewed and experiments performed to verify. Stay tuned...

However, Pluto is still not a planet.

A few nine-year-olds will send me hate mail now...Smiley

It could be time to bid the Big Bang bye-bye. Cosmologists have speculated that the Universe formed from the debris ejected when a four-dimensional star collapsed into a black hole — a scenario that would help to explain why the cosmos seems to be so uniform in all directions.

The standard Big Bang model tells us that the Universe exploded out of an infinitely dense point, or singularity. But nobody knows what would have triggered this outburst: the known laws of physics cannot tell us what happened at that moment.

“For all physicists know, dragons could have come flying out of the singularity,” says Niayesh Afshordi, an astrophysicist at the Perimeter Institute for Theoretical Physics in Waterloo, Canada.

It is also difficult to explain how a violent Big Bang would have left behind a Universe that has an almost completely uniform temperature, because there does not seem to have been enough time since the birth of the cosmos for it to have reached temperature equilibrium.

In our Universe, a black hole is bounded by a spherical surface called an event horizon. Whereas in ordinary three-dimensional space it takes a two-dimensional object (a surface) to create a boundary inside a black hole, in the bulk universe the event horizon of a 4D black hole would be a 3D object — a shape called a hypersphere. When Afshordi’s team modelled the death of a 4D star, they found that the ejected material would form a 3D brane surrounding that 3D event horizon, and slowly expand.

The authors postulate that the 3D Universe we live in might be just such a brane — and that we detect the brane’s growth as cosmic expansion. “Astronomers measured that expansion and extrapolated back that the Universe must have begun with a Big Bang — but that is just a mirage,” says Afshordi.

Nature: Did a hyper-black hole spawn the Universe?
Physics arXiv: Out of the White Hole: A Holographic Origin for the Big Bang

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Baruj Benacerraf...


The Nobel Prize in Physiology or Medicine 1980
Baruj Benacerraf, Jean Dausset, George D. Snell

Baruj Benacerraf

Born: 29 October 1920, Caracas, Venezuela

Died: 2 August 2011, Boston, MA, USA

Affiliation at the time of the award: Harvard Medical School, Boston, MA, USA

Prize motivation: "for their discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions"

I was born in Caracas, Venezuela, on October 29, 1920 of Spanish-Jewish ancestry. My father, a self-made business man, was a textile merchant and importer. He was born in Spanish Morocco, whereas my mother was born and raised in French Algeria and brought up in the French culture. When I was five years old, my family moved to Paris where we resided until 1939. My primary and secondary education was in French which had a lasting influence on my life. The second World War caused our return to Venezuela, where my father continued to have a thriving business. It was decided that I should pursue my education in the United States, and we moved to New York in 1940. I registered at Columbia University in the School of General Studies, and graduated with a Bachelor of Science Degree in 1942, having also completed the pre-medical requisites for admission to Medical School. By that time, I had elected to study biology and medicine, instead of going into the family business, as my father would have wanted. I did not realize, however, that admission to Medical School was a formidable undertaking for someone with my ethnic and foreign background in the United States of 1942. In spite of an excellent academic record at Columbia, I was refused admission by the numerous medical schools I applied to and would have found it impossible to study medicine except for the kindness and support of George W. Bakeman, father of a close friend, who was then Assistant to the President of the Medical College of Virginia in Richmond. Learning of my difficulties, Mr. Bakeman arranged for me to be interviewed and considered for one of the two remaining places in the Freshman class. I was accepted and began my medical studies in July 1942. While in medical school, I was drafted into the U.S. Army with the other medical students, as part of the wartime training program, and naturalized American citizen in 1943 I greatly enjoyed my medical studies, which at the Medical College of Virginia were very clinically oriented. I received what I considered to be an excellent medical education in the relatively short time of three war years.

Nobel Prize:

Biography, Lecture

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Multiple Personality Material...



Photo: In order to understand how complex materials merge at the boundary, scientists look at cross-sections of an oxide superlattices. In this picture, peaks correspond to layers of cuprate superconductor and valleys to metallic manganites (bottom region). The power of scanning tunneling microscopy allows researchers to gain insight into both the material's topography as well as its electronic properties.

ARGONNE, Ill. – Just like people, materials can sometimes exhibit “multiple personalities.” This kind of unusual behavior in a certain class of materials has compelled researchers at the U.S. Department of Energy’s Argonne National Laboratory to take a closer look at the precise mechanisms that govern the relationships between superconductivity and magnetism.

Previous measurements of magnetic and electronic properties in these superconducting oxide materials relied on aggregate or “bulk” measurements of a large area. By using advanced scanning tunneling microscopy at the laboratory’s Center for Nanoscale Materials, Argonne physicist John Freeland and materials scientist Nathan Guisinger were able to develop a clearer picture of the physical and chemical behavior of boundary regions within the material.

According to Guisinger, the most important regions of study in oxide superconductors are the boundaries or interfaces.

“You can think of the sample as kind of like lasagna,” Guisinger said. “There are layers within it that have different properties, and we want to see if the ‘cheese’ in one section mixes with the ‘sauce’ in another.”

Argonne National Laboratory: A Material's Multiple Personalities

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Luis Alvarez...



The Nobel Prize in Physics 1968
Luis Alvarez

Born: 13 June 1911, San Francisco, CA, USA

Died: 1 September 1988, Berkeley, CA, USA

Affiliation at the time of the award: University of California, Berkeley, CA, USA

Prize motivation: "for his decisive contributions to elementary particle physics, in particular the discovery of a large number of resonance states, made possible through his development of the technique of using hydrogen bubble chamber and data analysis"

Field: Particle physics

Luis W. Alvarez was born in San Francisco, Calif., on June 13, 1911. He received his B.Sc. from the University of Chicago in 1932, a M.Sc. in 1934, and his Ph.D. in 1936. Dr. Alvarez joined the Radiation Laboratory of the University of California, where he is now a professor, as a research fellow in 1936. He was on leave at the Radiation Laboratory of the Massachusetts Institute of Technology from 1940 to 1943, at the Metallurgical Laboratory of the University of Chicago in 1943-1944, and at the Los Alamos Laboratory of the Manhattan District from 1944 to 1945.

Early in his scientific career, Dr. Alvarez worked concurrently in the fields of optics and cosmic rays. He is co-discoverer of the "East-West effect" in cosmic rays. For several years he concentrated his work in the field of nuclear physics. In 1937 he gave the first experimental demonstration of the existence of the phenomenon of K-electron capture by nuclei. Another early development was a method for producing beams of very slow neutrons. This method subsequently led to a fundamental investigation of neutron scattering in ortho- and para-hydrogen, with Pitzer, and to the first measurement, with Bloch, of the magnetic moment of the neutron. With Wiens, he was responsible for the production of the first 198Hg lamp; this device was developed by the Bureau of Standards into its present form as the universal standard of length. Just before the war, Alvarez and Cornog discovered the radioactivity of 3H (tritium) and showed that 3He was a stable constituent of ordinary helium. (Tritium is best known as a source of thermonuclear energy, and 3He has become of importance in low temperature research.)

Nobel Prize: Biographical, Nobel Lecture, Banquet Speech

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Quantum Algae...

Image of the diffraction grating made by the researcher

The exoskeleton of a tiny organism has been used as a diffraction grating by researchers in Vienna, who have carried out a molecular interferometry experiment using it. The team showed that a coherent molecular beam could be diffracted from the silicon-based cell walls of a marine alga. Algae are cheap and easily available, so replacing costly nanodevices with them in interferometry experiments would be beneficial, according to the researchers.

Contrary to classical mechanics, quantum physics states that a particle can act like a wave and vice versa – an idea that was first proposed by Nobel-prize-winning physicist Louis de Broglie back in 1923. While the idea that tiny particles such as electrons could behave like a wave came as a shock, scientists now know that even objects a million times more massive than electrons, such as complex molecules, also show quantum interference. Massive molecules have very small wavelengths and therefore a grating with extremely thin and closely spaced slits is needed to observe their diffraction. Currently, such sophisticated devices are specially fabricated using nanotechnology techniques.

Physics World: Diatoms bring the quantum effects to life

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