Featured Posts (3478)

Sort by

Excerpt- Vacuum Draft Flows Part I

Although the following novella excerpt is in a separate universe from DARK EDGE, I've still been considering publishing within the next few months once the design portion of DARK EDGE has slowed down.

Excerpt- Vacuum Draft Flows Part I

"CHAPT 3

                Green means go and the seconds in between become an infinite and hopeless abyss. The abyss consumed the fears, hopes and dreams of all who found themselves in its presence. Regret, that so many things have been left undone and too many things left unsaid. Pain, that there are no more opportunities and this is the absolute end of all things. Finally, bliss once a man or woman can sweat pure adrenaline and testosterone fuels superhuman strength and senses. Human eyes adjust to slits, brows are frowned, teeth are grit and ground into dust, fingers tremble to crush metal held by throbbing palms, muscles twitch and spasm begging for immediate use. Death is but a weak ghost afraid to take the souls due to him, souls so powerful in this moment that even the reaper couldn’t pull them into the abyss before they willingly conceded to perish.

“Fuck Death” whispered Celia.     "

Want to know more? Stay tuned spacefans!

Read more…

NanoVelcro...

Courtesy: ACS Nano DOI: 10.1021/acsnano.7b03073

Topics: Biology, Bioengineering, Nanotechnology

For any couple who has witnessed an amniocentesis with WIDE eyes (as I did), this advance should be a welcome relief.

Circulating fetal nucleated cells (CFNCs) in the blood of pregnant women is an ideal source of fetal genomic DNA that can be used for prenatal diagnostics. However, the problem is that there are only a very small number of CFNCs in maternal blood. A team of researchers in the US, China and Taiwan has now developed nanoVelcro microchips that can effectively enrich a subcategory of CFNCs, namely circulating trophoblasts (cTBs) in blood samples. These cTBs can then be isolated using a laser microdissection technique for subsequent genetic testing.

Current prenatal tests for diagnosing foetal genetic abnormalities rely on invasive, “harvesting” procedures, such as amniocentesis and chorionic villus sampling. Although highly valuable, they can increase the risk of miscarriage. Whole foetal cells circulating in an expectant mother’s blood could also provide important information on foetal DNA since they contain entire genomes, but until now it has been very challenging to capture these cells because they are only present in small quantities.

The new nanoVelcro microchips developed by Hsian-Rong Tsung of the California NanoSystems Institute at the University of California at Los Angeles and colleagues can effectively enrich cTBs from blood samples. These cells can then be isolated using a technique called laser capture microdissection (LCM) for subsequent genetic testing.

The researchers (who initially developed their microchips for detecting low concentrations of tumour cells circulating in blood) made their devices by nano-imprinting them on a spin-coated PLGA substrate (see image). To enrich the cTBs, they grafted a biotinylated anti-EpCAM (which is a trophoblast surface marker) onto the imprinted nanoVelcro.

For the genetic characterization, they isolated at least three individual cTBs and pooled these together in a 0.5 mL polymerase chain reaction (PCR) tube for whole genome amplification (WGA). They then subjected the resulting amplified DNA to so-called array comparative genomic hybridization (array CGH) and short tandem repeat (STR) assays.

NanoVelcro microchips for prenatal testing, Belle Dumé, Nanotechweb.org
Read more…

Jupiter's Northern Lights...

A complete reconstruction of what the northern and southern auroras looked like to the Juno Ultraviolet Spectograph (UVS) as Juno approached Jupiter, passed over the north pole, rapidly traveled to the southern hemisphere to pass over the southern pole, and receded from Jupiter. Credit: BERTRAND BONFOND.

Topics: Astronomy, Astrophysics, Planetary Science, Space Exploration

Evidence from the Juno probe’s close flights past Jupiter indicate that the gas giant’s dazzling polar light shows are caused by a mysterious mechanism different from the one responsible for intense auroras here on Earth.

On Jupiter, as on Earth, the northern and southern lights are produced by charged particles from the Sun colliding with gas atoms in the atmosphere and releasing energy in flashes of light.

Jupiter’s aurora is the brightest in the solar system, so planetary scientists assumed it was produced by the discrete process.

However, a paper in Nature analyzing data from Juno’s low-altitude passes over Jupiter’s poles shows that, while there are extremely intense electric fields aligned with the magnetic field and signs that electrons are being accelerated downwards, the resulting auroras were much dimmer than those produced by the broadband process.

Why? The authors don’t know, though they speculate that Jupiter’s intense auroras may be started by a discrete process creating a stream of electrons that is then disrupted and diffused by the magnetic field fluctuations that produce the broadband process.

Power supply for Jupiter’s aurora puzzles scientists, Michael Lucy, COSMOS magazine
Read more…

Minuscule to Immense...

Artwork by Ana Kova

Topics: Astrophysics, Big Bang, Neutrinos, Particle Physics, Theoretical Physics

In particle physics, scientists study the properties of the smallest bits of matter and how they interact. Another branch of physics—astrophysics—creates and tests theories about what’s happening across our vast universe.

While particle physics and astrophysics appear to focus on opposite ends of a spectrum, scientists in the two fields actually depend on one another. Several current lines of inquiry link the very large to the very small.

The seeds of cosmic structure
For one, particle physicists and astrophysicists both ask questions about the growth of the early universe.

In her office at Stanford University, Eva Silverstein explains her work parsing the mathematical details of the fastest period of that growth, called cosmic inflation.

“To me, the subject is particularly interesting because you can understand the origin of structure in the universe,” says Silverstein, a professor of physics at Stanford and the Kavli Institute for Particle Astrophysics and Cosmology. “This paradigm known as inflation accounts for the origin of structure in the most simple and beautiful way a physicist can imagine.”

Scientists think that after the Big Bang, the universe cooled, and particles began to combine into hydrogen atoms. This process released previously trapped photons—elementary particles of light.

The glow from that light, called the cosmic microwave background, lingers in the sky today. Scientists measure different characteristics of the cosmic microwave background to learn more about what happened in those first moments after the Big Bang.

According to scientists’ models, a pattern that first formed on the subatomic level eventually became the underpinning of the structure of the entire universe. Places that were dense with subatomic particles—or even just virtual fluctuations of subatomic particles—attracted more and more matter. As the universe grew, these areas of density became the locations where galaxies and galaxy clusters formed. The very small grew up to be the very large.

Scientists studying the cosmic microwave background hope to learn about more than just how the universe grew—it could also offer insight into dark matter, dark energy and the mass of the neutrino.

What can particles tell us about the cosmos?The minuscule and the immense can reveal quite a bit about each other.Amanda Solliday, Symmetry Magazine
Read more…

I have a pre-order that needs some reviews.

Hey BSFS community!

If you're familiar with my work, then you've probably heard of "Squirrels & Puppies" and "Flowers & Kittens".  They're short story collections of the weird, dark, and slightly humorous.  I like dealing with the ideas of race, religion, and morality, and in this new book, "Hugs & Bunnies: Weird and Dark Tales", the nature of God will be one of the themes.  He's going to be symbolized as a giant robot, a sex doll, and a bunch of blue flowers among other things in this book of short stories. 

It's available for pre-order, and it needs some reviews.  I'll happily send you a free copy in exchange for a review.  It comes out on December 1st.  Oh, before I forget:

WARNING: SCENES OF GRAPHIC VIOLENCE.

There ya go.  Thanks again BSFS!

Read more…

Fall Into Literacy Community Book Festival

 
MG Hardie will attend Los Angeles' 7th Annual Fall Into Literacy Community Book Festival!
This year’s theme, Viva Los Libros, will promote literacy, education, and basic-need resources through honoring our community’s diverse heritage.
This is a free literacy event and this year, we plan to bring you even more excitement by featuring exhibitors with reading and writing-related children’s activities, performances, live authoring readings and more! Stay tuned for announcements on special guests scheduled to attend.
As an attendee, you will learn the importance of literacy in our everyday lives along with tips and resources to help your children with literacy. Together, we can inspire not only a child, but a whole community to love to read and write.
Read more…

Almost Cliché...

Satellite Image of Hurricane Irma from Space, Space.com

Topics: Climate Change, Economy, Green Tech

I saw "An Inconvenient Sequel" about a month ago. It's almost cliché to use the term "super storm," or in our case of so soon on the heels of Harvey in Texas with Irma in Florida, plural. I blogged about it. I ate popcorn. I conveniently compartmentalized its warnings until now. My apathy is we haven't changed one iota since Katrina or Rita. Cliché storms, starving polar bears, the Antarctic glacial sheet melting...we appear to be ready for football and the next chapter of the Kardashians. I am as concerned for family and friends in Florida as I was in Texas, bracing for the next cliché; before the end of hurricane season and the beginning of the winter ahead. Whether bitter or mild, it will not be "normal."

As with my advocacy of green tech (and anything tech), I can see one clear benefit for fighting climate change: employment. It more than incarceration tends to guarantee stable societies. The coal jobs that used to sacrifice human life and limb as well as a few drilling jobs for the most part are now done by robots. Europe and other countries are not letting "grass grow under their feet" technologically speaking. Chancellor Angela Merkel seems determined for Germany to occupy that well-deserved space as (now) leader of the free world will indeed be a woman...just not an American.

I follow many blogs, Stone Kettle Station being a gem. I almost titled this post with a cliché/expression Jim Wright used in this posting: "Creationists don't build starships." Neither will we, at this point in our technologically lazy history. I say lazy in the sense one does not fabricate a "science" out of whole cloth when the results of observation and experiment reported by the actual subject makes you uneasy. Advocating for it to be taught next to actual science K-12 is galling. It propels us from Democracy to Idiocracy, no suspended animation required.

We're already on a spaceship called Earth without the need to create fantastic engine drives or exotic technologies. It's power source is a fusion reactor at the center of our solar system, it likely forming some distance from here in a star cluster (and a twin sister), along with the precious metals we esteem so highly. Our ship travels space in 365.25 day increments as the system travels the Milky Way as the Milky Way traverses the existing stars, many we have not observed and only discover as we meander the Cosmos. In this sense, we're all astronauts. As such, we're on a ship with a volume, mass and density. It can only give limited supplies of fuel, food and resources. Some of us hoard resources and abuse ship supplies. To compartmentalize those resources, we demarcate ourselves as rich, poor, black, white, makers, takers, winners, losers, deserving, not deserving; human...NOT human. Eventually vessels give way to the wear-tear of Entropy. As one of the lessons of the Titanic attests, even the strongest of bows will break on blunt and obvious icebergs. Captain Ahab is cultural metaphor, known without reading Melville's long novel, a byword and proverb of obsession leading to destruction by relentless natural forces, the leviathan a phallic symbol.

To quote President Bush verbatim: "we're addicted to oil." Our world economy became global on the gold of cotton picked by slaves. Now we're beholden to the value of the dollar and OPEC futures. We would have to halt production full-stop and leave current fossil fuels in the ground, according to The Guardian: our gasoline, Vaseline, plastics, mobile phones, automotive and apparel industries aren't about to let that happen. Controlling the media to the point that an Australian billionaire and a Saudi Prince dictate the thoughts of ditto heads on a media conglomerate 21 years old such that denialism has an obvious profit motive. "Good to the last drop" was a Maxwell House tag line, and may well be our epitaph.

The passengers of the Arbella who left England in 1630 with their new charter had a great vision. They were to be an example for the rest of the world in rightful living. Future governor JOHN WINTHROP stated their purpose quite clearly: "We shall be as a city upon a hill, the eyes of all people are upon us." Source: US History

That famous line has been quoted and paraphrased by President Reagan and recently former FBI Director James Comey. Rather than that puritan and idealistic view of our percentage of humanity and rose-colored view of history, we currently behave metaphorically like the survivors of a shipwreck... on a dung heap.
Read more…

Festival of Great Literary Reads

The Festival Of Great Reads understands the importance of children developing a love for reading. This is a great time to get new books before the school year begins and meet the authors of these awesome reads.

 

There will be a panel of authors, including award-winning authors Maritere Belles and Natalie Torres discussing "How to get your child to read." & "How to encourage your young writer."

 

This FREE family event is sure to be epic so you don't want to miss it. Come out and enjoy a day of literacy, music, face painting, food, and raffle prizes.

 

 

 

2209 East 6th Street

Corner of 7th & Junipreo

Long Beach, CA 90814 

Sat, August 26, 2017

10:00 AM – 3:00 PM PDT

 

Read more…

Quantum Light on a Chip...

A laser (green) excites the quantum dot (red) in this diagram of the chip. The ring, which is tuned via applying voltage to the yellow contacts, manipulates the characteristics of individual photons (ellipsoids).
Topics: Laser, Nanotechnology, Photonics, Quantum Dots, Quantum Mechanics, Solid State Physics

Ideally, optical circuits would generate and shuttle light so well that researchers could use them to transmit encoded information, sense chemical species, and perform quantum computations. But because the components for each circuit—light sources, mirrors, splitters, filters, and waveguides—occupy several feet of table space, they cannot manipulate light down to the nanoscale. In an effort to downsize components and produce practical quantum photonic devices, researchers have been tinkering with nonlinear materials, atomic defects, and traditional semiconductors at the nanoscale.

Now Ali Elshaari at KTH Stockholm and his colleagues have taken a major stride by embedding circuit components on a CMOS-compatible chip that takes up a millionth the area of a tabletop apparatus. The key innovation was implementing precise control over quantum dot light sources, which emit photons in specific quantum states, including entangled ones, when excited by lasers. Scientists had struggled to control the dots’ emission and integrate the dots with waveguides for on-chip applications. Elshaari’s team devised a special geometry that optimized the alignment of the dots’ light emission with the fundamental waveguide mode, which resulted in high coupling efficiencies. To control the emission, an electrically tunable device acted as a spectral filter that could fine-tune the photon characteristics.

Manipulating quantum light on a chip, Katyayani Seal, Physics Today
Read more…

Nanoscale Quantum Memory...

Electron microscope image of the optical cavity used to make a quantum memory. Each segment in the cavity has a vertical dimension of about 690 nm (Courtesy: Tian Zhong et al / Science)
Topics: Modern Physics, Nanotechnology, Quantum Computer, Quantum Mechanics

A new type of optical quantum memory that could be integrated with other components on a chip has been unveiled by physicists in the US. The device overcomes an important challenge facing researchers trying to make quantum computers based on light – how to efficiently capture a photon within a sub-micron-sized structure.

From sending messages that could never be bugged to linking together quantum computers in a "quantum Internet", the ability to exchange quantum information may be vital to the future of technology. This will not be possible, however, without quantum memories to store quantum states and release them when needed.

In the Internet of today, information is sent between computers through a distributed series of nodes called routers. "Packets [of information] are maybe stored for some time and then they are sent," says Andrei Faraon of the California Institute of Technology, "There is some control over the timing of the packet." An optical network that uses photons to carry quantum information would require analogous nodes to store not strings of ones and zeroes (bits) but the full quantum states of individual photons (quantum bits or qubits).

There are currently several different quantum memories under development – some storing qubits as collective excitations in ensembles of atoms, others using solid-state crystals. Among the second group, crystals doped with ions of rare-earth metals have proved successful because rare-earth ions have sharp, stable electronic transitions that can couple to photons and preserve their quantum states. However, absorbing a photon generally requires millimetre- to centimetre-thicknesses of material, making quantum memories rather large.

Optical quantum memory shrinks to the nanoscale, Tim Wogan, Physics World
Read more…

Design materialized as the next logical step

The mind space, similar to toothpaste. In the tube it can be squeezed and mangled within the confines of it's container. Remove the cap and out it comes but according to a little coaxing and the now unblocked orifice. The point is managing the next logical outcome. Then envisioning how far you can take that outcome. I've have seen geodesic domes made of Saran Wrap, bubble wrap and Plexiglas but I wouldn't live in any of them. The mind can conceive so much. Practicality is often based on economics and availability even before you get to durability and aesthetics. The famous Frank Lloyd Wright while on the cutting edge of style and grace made an eventually leaky dwelling because the materials available didn't perform as planned (pushed too far). I've seen cargo container home designers give up and coin the industrial/shipyard look as cool, trendy, hip, NOT! Think that's bad try the military look, not to diss the military, after all they did glamorize the one thing that works well, 'camouflage'. In architecture it is called facades. In fashion it is costume and makeup, in culinary it's substitute and seasoning. Look and feel of one thing while having the structure and substance of something else.....but you know how many Naugahydes it takes to simulate deep Corinthian leather? A full 10 gallon pail (that's hat in Texas).

Yes, this is an exercise in design, the next logical assumption. Every step wither back, to the side or to jump ahead leads somewhere. Strip the rippled walls off a cargo container and cover the frame in glass. Double the glass and fill the gap with Styrofoam beads, coat with Ray-ban, electric phase change salts, roll down screens. Curve the glass into a quonset covering. You can seal this or make it slide like a pool cover. Under the quonset the space is open, forget the horse barn and barrack look. I've seen private jets that have near the same shaped space so plush it's like Star Trek. The airship or future blimp has sliding vista windows and roofs, a strolling isle like a fashion show walkway, accommodations, build-ins, no wasted space, and no clutter, an observation deck with a bar, sleeping state rooms. Talk about leisure cruises.

Young folks are living in smaller spaces so they can afford the luxury. It is a mind-space trade off. JUST THINK, take "da lux" off your SUV and outfit your tiny house, haul it with a beater truck and look like stepping off a "Lost in Space" episode before Dr. Smith becomes Mr. Smith, the real one in the Matrix. All Smiths find out, this is why black Smiths live off world, "Nubian I think". Morpheus is one of the Jones boys but "The Rock" is a Johnson like me (no relation and yet I wonder).        

Read more…

Diabolo...

Image Source: Link below
Topics: Geometry, Mathematics, Optical Physics

A ring-shaped optical cavity has degenerate resonant modes, because clockwise and anticlockwise waves resonate at the same frequencies. The degeneracy can be lifted, and the frequencies split, by a perturbation such as a physical rotation or the presence of a molecule or nanoparticle. Typically, the frequency splitting is proportional to the perturbation’s magnitude, as illustrated in the top panel of the figure for a hypothetical complex-valued perturbation ε (that is, one that can affect both the light’s frequency and its phase). Because the plot’s shape resembles a yo-yo-like toy called a diabolo, the degeneracy has been dubbed a diabolic point. The mode splitting around a diabolic point is the basis for optical gyroscopes, and it’s been explored for other sensing applications.

There’s another type of degeneracy, called an exceptional point, where not only do resonant frequencies coincide but their resonant modes do too. In the case of the ring resonator, inserting reflectors to scatter light from the anticlockwise mode into the clockwise mode (but not vice versa) creates an exceptional point with a single resonant mode, the clockwise-traveling wave. Perturbing the system splits that mode into two resonances, each with a small admixture of the anticlockwise wave, and the frequency splitting scales with the square root of the perturbation magnitude, as shown in the bottom panel.

Exceptional points make for exceptional sensorsAt just the right locations in parameter space, resonant frequencies are ultrasensitive to tiny changes.Johanna L. Miller, Physics Today
Read more…

Phase II Transitions...

Image Source: An article on LinkedIn by Linda Morales
Topics: Commentary, Education, Nanotechnology, STEM

In the post Transitions, I alluded to I might not be posting as regularly due to the rigors of graduate school. Well that rigor came last week and this week. I'm getting my footing on homework, collaboration and time management. The faculty, staff and student body here are the picture of diversity. I've literally met people from around the globe and not once have I repeated a country on our introductions. Ghana...Korea...Iran...Saudi Arabia...Sudan...Sweden...et al and each when I said I grew up in Winston-Salem (30 minutes west on I-40) and I'm an alumni of the university, they have without fail stated: "you came home."

I re-acclimated myself to the new F.D. Bluford Library. It's much larger with three floors, the top being the quietest place to study in. The librarians said I'd be there a lot, reading the papers my professors published in journals, of which they have a lot of from American, Indian, Chinese journals as well as from professional technical societies if memory serves. The old Bluford was renamed in honor of my Chancellor Edward Fort as a research and grant center. He's still around, and teaching as well as Dr. Casterlow (my karate and calculus instructor - retired) and Dr. Sandin, who's taught at A&T since 1968. He taught Dr. Ron McNair his first physics class, as he had taught mine. After 50 years of honorable and distinguished service, he'll retire next year.

One of the things I got over quickly was being an older graduate student. I saw some during graduate orientation that at least looked distinctly older than me. No one has made me feel uncomfortable, and the chair of the Nanoengineering Department said I wasn't his oldest student (I asked). He graduated a PhD last year at the ripe young age of 63. He's working as a director in industry. There's hope.

I've joined the Nano Energy group as my research area of concentration. I interviewed the principle investigators in that and the nano-wire/photonics group before I made my decision, both areas tempting and equally interesting. I felt energy was a good fit for my industry experience, science and social interests and my inclinations to do something that makes the world a better place.

I also share Dr. Cho's ambition of getting more African Americans into batteries and by extension STEM fields: the New York Times published an article stating even with Affirmative Action, African Americans, Hispanics/Latinos lag behind all other groups since I was an undergrad. I recall 1980 was supposedly the largest number of African American males attending colleges and universities, noted again by the New York Times in a 2002 related article, observing more sadly are inmates. I speculate the impacts of globalization, adolescent pregnancies and inadequate educational resources (see NYT article, second link) keeps societal stratification darkly and remarkably intact.

The JSNN (Joint School of Nanoscience and Nanoengineering) has a "nano-bus" they use to do K-12 outreach. It's a teaching requirement for PhD students (that can also be fulfilled by grading papers or teaching a class or lab), so I volunteered. I was respectfully declined as this is my first semester, and the graduate coordinator wants us to focus on setting a good foundation to be successful. After my fire hose days, I can see the importance. When it's appropriate (i.e., I've successfully managed time and the fire hose), and for reasons I hope I've made you understand, I'll be getting on that bus.
Read more…
Photograph of a sapphire wafer that is patterned with the photonic bandgap resonators used in this work. It shows two full devices and parts of four others. Before using them in experiments they are cut out of the array and wired up. The devices themselves are about 1 cm long. The serpentine structures are microwave Bragg mirrors and the straight lines of varying width at the center of each device are the microwave cavities. Courtesy: A Sigillito

Topics: Electromagnetism, Solid State Physics, Quantum Dots, Quantum Mechanics

Researchers at Princeton University and the Lawrence Berkeley National Laboratory have succeeded in controlling nuclear spins in silicon by purely electrical means. Until now, electronic or nuclear spins could only be manipulated through radio-frequency magnetic fields. The feat could help in the development of quantum processors based on nuclear spin qubits.

Classical computers store and process information as "bits" that can have one of two logic states ("0" or "1"), but quantum computers work on the principle that a quantum particle (such as an electron or atomic nucleus) can be in two states at the same time – "spin up" or "spin down". These two spin states represent a logical "1") or a "0", so N such particles –or quantum bits (qubits) – could be combined or "entangled" to represent 2N values simultaneously. This would lead to the parallel processing of information on a massive scale not possible with conventional computers.

In practice, it is difficult to make even the simplest quantum computer, however, because these quantum states are fragile and are easily destroyed. They are also difficult to control. For a qubit to work, it should thus be well isolated from its environment to preserve its quantum properties, and prevent "decoherence". At the same time it should be robust enough so that its state can be read out and manipulated. The intrinsic magnetic moment of an atomic core, or nuclear spin, is a good qubit candidate in this respect because it fulfills all of these criteria.

There is a problem, however, in that the magnetic moment of a nuclear spin is 10 billion times smaller than the moment of one bit of a modern hard drive, and it is almost impossible to detect, let alone manipulate, such a tiny signal.

Electric fields control nuclear spin qubits in silicon, Belle Dumé, Nanotechweb.org
Read more…

My name is Kenneth James, and I am currently editing the personal journals of the renowned SF writer Samuel R. Delany in a multivolume series for Wesleyan University Press.  The first volume, In Search of Silence -- which collects Delany's journals from the 1960s -- has, since its publication earlier this year, received very positive reviews from such venues as The New Republic, The Gay & Lesbian Review, and the Barnes & Noble column by SF critic Paul Di Filippo.  Here are links to two of these (the G & L Review article is unfortunately behind a paywall):
The next volume, which I'm working on now and which is entitled Autumnal City, collects Delany's personal journals from the '70s -- during which time Delany wrote some of his most groundbreaking work, including Dhalgren, Trouble on Triton, and Tales of Neveryon.  During this time he also did substantial preliminary work for the novel Stars in My Pocket Like Grains of Sand.
I've just launched a crowdfunding campaign at Indiegogo to fund the completion of Autumnal City.  Here is a link to the campaign page; do check it out if you'd like to learn more about the project:

Please help spread the word about this campaign!

Read more…

3D Living Tissue...

Image of the 3-D droplet bioprinter, developed by the Bayley Research Group at Oxford, producing mm-sized tissues Credit: Sam Olof/ Alexander Graham
Topics: 3D Printing, Additive Manufacturing, Biology

Scientists at the University of Oxford have developed a new method to 3D-print laboratory- grown cells to form living structures.

The approach could revolutionize regenerative medicine, enabling the production of complex tissues and cartilage that would potentially support, repair or augment diseased and damaged areas of the body.

In research published in the journal Scientific Reports, an interdisciplinary team from the Department of Chemistry and the Department of Physiology, Anatomy and Genetics at Oxford and the Centre for Molecular Medicine at Bristol, demonstrated how a range of human and animal cells can be printed into high-resolution tissue constructs.

A confocal micrograph of an artificial tissue containing 2 populations human embryonic kidney cells (HEK-293T) printed in the form of an arborized structure within a cube Credit: Sam Olof / Alexander Graham

Interest in 3D printing living tissues has grown in recent years, but, developing an effective way to use the technology has been difficult, particularly since accurately controlling the position of cells in 3D is hard to do. They often move within printed structures and the soft scaffolding printed to support the cells can collapse on itself. As a result, it remains a challenge to print high-resolution living tissues.

A new method for the 3-D printing of living tissues, Alexander D. Graham et al. High-Resolution Patterned Cellular Constructs by Droplet-Based 3D Printing, Scientific Reports (2017). DOI: 10.1038/s41598-017-06358-x, Phys.org
Read more…

White Bored!

The driving force behind this comic book gaming adventure is the Black experience.  Their conflicting hopes, dreams and visions of a better future and a brighter tomorrow are dramatized in a scintillating voyage between comic books and video games.  Move over pop culture dinosaurs, Ultimate Voyages promises to restore its readers, gamers and adventurers to their rightful place.  No more sitting in the balconies or at the back of the bus.  Its novelty is in its reimagining the world or the United States, for that matter, as the home of the free and land of the slave.  It delivers a stretch of storylines and character building levels that are fun and engaging for those brave enough to enter its dimension.  The story ventures out with Ultimate Voyages through Language and History, followed by its sequel The UHURU Initiative: Revenge of the White Gaud, then drops you in the driver’s seat in a World of Ultimatums, pulling you back in with the yet to be released title Courage to Succeed.  Created and produced by a private individual fed up with the lack of inclusion and connection he felt with popular culture.  

Read more…

Appomattox Legacy...

Topics: Civics, Civil Rights, Commentary

Today is my 55th birthday. I start graduate classes today. I'd hoped to be in a better mood, an uplift from Friday's post.

Saturday, I watched the events in Charlottesville, Virginia unfold on national television. My wife cried even before the name of the victim run over by a coward was announced. I'm sure her as well as my own thoughts drifted to our adult sons. My nephew opined about his own son, not even a year old and the world he and his girlfriend have to prepare him for.

I'm studying an exciting STEM field (Nanoengineering), but I find the living at my particular artificial societal demarcation of humanity exhausting. No one can convince me this isn't a mental disorder; a mass hysteria born of the first African American being elected president of the republic in 232 years and the backlash encouraged by right/Reich wing web sites, talk radio and schlock television hosts on conservative outlets. Despite having their chaos agent in power, this madness continues unabated.

I will study HARD. I think it's the only thing that will keep me calm...and sane.

I could only think of the post for Appomattox (April 12, 2015). I think it is apropos for our current and continuing neurosis on division, expanded via FOGHORN by our current "chief executive*", an obvious accident of a bereft national knowledge of civics responsibility.

His response to the violence Saturday he encouraged during the campaign was weak and tepid. An obvious dolt at history, he's never heard the quote made famous by Malcolm X "the chickens have come home to roost," (and he wasn't the origin of it, just its more modern proponent) now a double entendre of karma and irony.

One would think he was concerned about how his words would be measured by the Klan and Neo Nazis, and could care less what the rest of his nation thinks.

"To be a Negro in this country and to be relatively conscious is to be in a rage almost all the time." - James A. Baldwin

*****

NATIONAL PARKS SERVICE
Topics: #BlackLivesMatter, Civil Rights, Human Rights, Dred Scott, Walter Scott

Thursday, 9 April was the Sesquicentennial, the 150 year anniversary of the South's official surrender to the North in the person of Generals Robert E. Lee to Ulysses S. Grant in Appomattox, Virginia. On the same date in 1947, Branch Rickey signed Jackie Robinson, making him the first African American to play in major league baseball; the first professional athlete of color in any sport at the time. He walked through a door first opened by Jesse Owens at the 1936 Olympic Games, invalidating Hitler's theories of Aryan athletic superiority.

Yesterday, Walter Scott was buried...murdered in the heart of the Confederacy, for a broken tail light.

Cliven Bundy - that $1.1 million dollar, artful, tax-dodging welfare queen, who actually through armed militia threatened US officials with armed insurrection - is still free.

Dred Scott - the man for whom the Supreme Court's most daft decision was the match spark for the Civil War (and apparently, the nomination of Abraham Lincoln as candidate to the-then radical/progressive republican party) - said in the opinion of Chief Justice Taft:

"In the opinion of the court, the legislation and histories of the times, and the language used in the Declaration of Independence, show, that neither the class of persons who had been imported as slaves, nor their descendants, whether they had become free or not, were then acknowledged as a part of the people, nor intended to be included in the general words used in that memorable instrument...They had for more than a century before been regarded as beings of an inferior order, and altogether unfit to associate with the white race, either in social or political relations; and so far inferior, that they had no rights which the white man was bound to respect; and that the negro might justly and lawfully be reduced to slavery for his benefit." [1]

Hauntingly, Dred Scott is buried just miles outside of Ferguson, Missouri.

From a similar, thoughtful article in The Atlantic: "It is easy to proclaim all souls equal in the sight of God,” wrote James Baldwin in 1956 as the Civil Rights Movement took hold in America; “it is hard to make men equal on earth in the sight of men." [2]

Since the election and reelection of President Obama, it's apparent we've never stopped fighting the Civil War. As publicly directed towards him, there is an obvious visceral disdain for the part of the American electorate that he, by existing embodies. There has been since his two terms an increase in highly motivated hate groups; hate crimes; the escalation in murders (example by this recent affront), luckily caught on a citizen's smart phone. Some would say the president has encouraged this. However, I posit that it's not his encouragement, it is his presence in the Presidential Mansion - renamed The White House after a visit to President Theodore Roosevelt by Booker T. Washington, and the national backlash it ensued [3] - that is so offensive to those that don't want their place in the social hierarchy disturbed (wanting "their country back"). From Trayvon Martin, Jordan Davis, Renisha McBride, Eric Garner and now Walter Scott: the Facebook meme below sums up the anger and frustration felt by citizens of this country. [4] It means we can never relax, never just "be." Even our genetic telomere lengths are shorter due to this stress.

Over time, the Civil War became the subject of great romanticization and sentimentalism in cultural memory. For veteran soldiers on both sides, reconciliation required time and the pressure of political imperatives imposed by the larger society on them and on the conflict’s memory. In the wake of this war, Americans faced a profound and all but impossible challenge of achieving two deeply contradictory goals—healing and justice. Healing took generations in many families, if it ever came at all. Justice was fiercely contested. It was not the same proposition for the freedmen and their children as it was for white Southerners, in the wake of their military, economic and psychological defeat. And in America, as much as it sometimes astonishes foreigners, the defeated in this civil war eventually came to control large elements of the event’s meaning, legacies, and policy implications, a reality wracked with irony and driven by the nation’s persistent racism. [2]

Walter Scott sprinted from the scene of a traffic stop, possibly thinking he was to be served for neglected child support payments. That is not worthy of an execution. He was shot in the back with the same regard as cattle at a slaughter shop; killing a mad dog fleeing. Considering that I am a US citizen that trained in a STEM field, an armed forces veteran (as Walter Scott); a MAN: I, nor my sons (the oldest also a veteran) should feel like this in our own country:

The "United" States of America: You cannot be united if you still support the slavery historically-generated "states rights" in everything from voting rights for African Americans; criminalizing a woman's right to choose, to same-sex marriage. The Ku Klux Klan; the John Birch Society; the Tea Party are the typical regressive reactionary responses to any fairness; any progress from the "lesser classes" that should "know their places." [5] We are becoming a byword; an oxymoron. The global economy we encouraged we're falling woefully behind. Technologically backpedaling, we are contesting Darwin and "Creation Science"; anti-vaccination activists to actual scientists; the Jesuit 6,000 year estimate to actual red shift measurement of the age of the universe; climate disruption that the Pentagon sees as an existential threat snowball poo-pooed as pseudo-controversy: our competition abroad has no equivalent analog - our inanity is being ignored for good reason. Like ancient Rome, we're bloated and over-extended; intensely tribal and superstitious; pseudo-scientific; withering from within. We are now a de facto Oligarchy, the only thing we're lacking is the final, deafening crash on the heaps of feudalism and anachronism. We could avoid it by an evolution in thought and policy; a new Appomattox that reinvigorates the republic, and takes this country forward: our viability as a nation is really in the long run, what matters for us all.

"We must learn to live together as brothers, or perish together as fools."
Dr. Martin Luther King, Jr.

1. This Day in Quotes: March 6, 1857, The Dred Scott Case2. The Atlantic: The Civil War Isn't Over, David W. Blight3. Slavery by Another Name: The Re-Enslavement of Black Americans from the Civil War to World War II, Douglas A. Blackmon4.
5. The Reactionary Mind: Conservatism from Edmund Burke to Sarah Palin, Corey Rubin
Read more…

Madness and Hiroshimas...

On August 6, 1945, 8.15 am, the uranium atom bomb exploded 580 meters above the city of Hiroshima with a blinding flash, creating a giant fireball and sending surface temperatures to 4,000-C. Fierce heat rays and radiation burst out in every direction, unleashing a high pressure shockwave, vaporizing tens of thousands of people and animals, melting buildings and streetcars, reducing a 400-year-old city to dust. [1]
Topics: Commentary, Existentialism, Politics

"Fire and fury"...that sounds tough until you denigrate 755 career diplomats an adversary expels in a retaliatory move for [them] interfering in our last election cycle. 755 professionals, their families...and children that will be displaced stateside just as schools are starting. It sounds strong, but when Kim Jong Un thinks it's crazy, it likely is. There will be no "cost savings" or reduction to any payroll, as unbeknownst to most of us, Moscow hasn't raised their flag above our capital (yet). It's an obvious dodge, diverting attention from the ongoing Russia investigation, "playing chicken" with extinction for an ego; the plot for a poorly scripted reality show we're all haplessly in.

We cannot continue "government by tweet and bluster." We cannot call ourselves a federal republic when our leader undermines his own citizens. We cannot continue as a nation, a PLANET or a species.

He was aptly described as a "chaos agent" during the primaries. He proves it daily.

The Atomic Bombings of Hiroshima and Nagasaki killed about 250.000 people and became the most dreadful slaughter of civilians in modern history. However, for many years there was a curious gap in the photographic records. Although the names of Hiroshima and Nagasaki were incised into our memories, there were few pictures to accompany them. Even today, the image in our minds is a mixture of devastated landscapes and shattered buildings. Shocking images of the ruins, but where were the victims?

The American occupation forces imposed strict censorship on Japan, prohibiting anything "that might, directly or by inference, disturb public tranquility" and used it to prohibit all pictures of the bombed cities. The pictures remained classified 'top secret' for many years. Some of the images have been published later by different means, but it's not usual to see them all together. This is the horror they didn't want us to see, and that we must NEVER forget: [1]

Image Source: [1]
Housewives and children were incinerated instantly or paralysed in their daily routines, their internal organs boiled and their bones charred into brittle charcoal. [1]

The atomic bombs dropped on Hiroshima and Nagasaki (6 and 9 August 1945) were the first of their kind. "Little Boy" and "Fat Man"+ were their code nicknames. If this "fire and fury" bluster sounds "familiar," it was likely borrowed from this far more presidential source. 45's impressive uncle likely explained a lot of things to the young millionaire, but his by now well known infamously short attention span, he likely missed a few salient points. Half-life+ is measured in thousands of years, for example. The current yield of thermonuclear versus atomic devices has been proposed to not be measured in mere TNT or megatons, but Hiroshimas.

The pictures above are vile, ugly and a reflection of a dark part of our national soul. "Hindsight being 20/20 vision," our actions may have tragically been utterly and arrogantly unnecessary. [2] We have danced on the edge of this scalpel for three generations that has been the background for a field known as dystopian science fiction, until Carl Sagan's salient warning now bears the hindsight of prophesy. [3] "Duck and cover" drills have become a part of our history of gallows humor, as currently our two malignant narcissistic* heads of state act like prepubescent boys, comparing the size of their phallus symbols, erect and ejaculating like pyromaniacs over the fires of Armageddon. A universe as well as what's left of the Earth will go on.

Humanity: it's been a good run.

1. Hiroshima, the pictures they didn't want you to see, Fogonazas2. The Bomb Didn’t Beat Japan … Stalin Did - Have 70 years of nuclear policy been based on a lie? Ward Wilson, Foreign Policy3. “We've arranged a global civilization in which most crucial elements profoundly depend on science and technology. We have also arranged things so that almost no one understands science and technology. This is a prescription for disaster. We might get away with it for a while, but sooner or later this combustible mixture of ignorance and power is going to blow up in our faces.” Carl Sagan, The Demon-Haunted World - Science as a Candle in the Dark.

Related links:

How Do Nuclear Weapons Work? Union of Concerned Scientists*Malignant Narcissism: Collision of Two Personality Disorders, Rhonda Freeman Ph.D., NeuroSagacity, Psychology Today [Note: since I am not a psychiatric professional, this is not breaking the "Goldwater rule." I am merely a citizen observing the obvious.]No One Should Have Sole Authority to Launch a Nuclear Attack, by the editors of Scientific American, Policy & EthicsPowerful Pictures Show What Nuclear ‘Fire and Fury’ Really Looks Like, Rachel Brown, National GeographicTrump Doubles Down on Threats Against North Korea as Nuclear Tensions Escalate, Peter Baker, New York Times

#P4TC:

Catharsis... March 31, 2013M.A.D... July 20, 2014+Half-Life... August 5, 2016The Minutes... January 30, 2017The Physics of Doomsday... July 24, 2017
Read more…